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DeCS
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Descriptor English:
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1-Phosphatidylinositol 3-Kinase
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Descriptor Spanish:
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1-Fosfatidilinositol 3-Quinasa
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Descriptor Portuguese:
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1-Fosfatidilinositol 3-Quinase
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Synonyms English:
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Phosphatidylinositol 3-Kinase
Phosphatidylinositol-3-OH Kinase
PtdIns 3-Kinase
PI-3 Kinase
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Tree Number:
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D08.811.913.696.620.525
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Definition English:
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An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. EC 2.7.1.137. |
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History Note English:
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98; use 1-PHOSPHATIDYLINOSITOL 3-KINASE (NM) 1988-97
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Allowable Qualifiers English:
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Record Number:
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33469
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Unique Identifier:
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D019869
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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